潮田研のこれまでの研究業績を紹介します。日本語の著書はこちらから。
*Corresponding Author
発表論文
Kaiku Uegaki, Yuji Tokunaga, Michio Inoue, Seiji Takashima, Kenji Inaba, Koh Takeuchi, Ryo Ushioda*, Kazuhiro Nagata*
Cell Reports 42(7):112742 (2023)
Redox states in the endoplasmic reticulum directly regulate the activity of calcium channel, inositol 1,4,5-trisphosphate receptors
Caba, C., Ali Khan, H., Auld, J., Ushioda, R., Araki, K., Nagata, K., and Mutus, B. (2018)
Conserved Residues Lys(57) and Lys(401) of Protein Disulfide Isomerase Maintain an Active Site Conformation for Optimal Activity: Implications for Post-Translational Regulation.
Frontiers in molecular biosciences 5, 18 (2018)
Maegawa, K., Watanabe, S., Noi, K., Okumura, M., Amagai, Y., Inoue, M., Ushioda, R., Nagata, K., Ogura, T. and Inaba, K.*
The highly dynamic nature of ERdj5 is key to efficient elimination of aberrant protein oligomers through ER-associated degradation
Structure, 25:846-857 (2017)
Araki K*, Ushioda R, Kusano H, Tanaka R, Hatta T, Fukui K, Nagata K, Natsume T
A crosslinker-based identification of redox relay targets
Anal. Biochem. 1;520:22-26. (2017)
R. Ushioda, A. Miyamoto, M. Inoue, S. Watanabe, M. Okumura, K. Maegawa, K. Uegaki, S. Fujii, Y. Fukuda, M. Umitsu, J. Takagi, K. Inaba, K. Mikoshibad, and K. Nagata*
Redox-assisted regulation of Ca2+ homeostasis in the endoplasmic reticulum by disulfide reductase ERdj5
Proc Natl Acad Sci U S A. Oct 11;113(41): E6055-E6063(2016)
この論文は産経新聞（2016年10月3日付23面)、京都新聞（2016年10月1日付33面）、共同通信、日経プレスリリースで報道された。
京都産業大学プレスリリース、理化学研究所プレスリリース (京産大へリンク)、東北大学プレスリリース、JSTプレスリリース
D.J. Klionsky*, K.Nagata, R.Ushioda et al.
Guidelines for the use and interpretation of assays for monitoring autophagy
Autophagy, 12(1): 1-222 (2016)
Kawasaki K, Ushioda R*, Ito S, Ikeda K, Masago Y, Nagata K*
Deletion of the Collagen-specific Molecular Chaperone Hsp47 Causes Endoplasmic Reticulum Stress-mediated Apoptosis of Hepatic Stellate Cells.
J Biol Chem. 290. 3639-3646 (2015)
Avezov E, Konno T, Zyryanova A, Chen W, Laine R, Crespillo-Casado A, Melo E, Ushioda R, Nagata K, Kaminski CF, Harding HP, Ron D*.
Retarded PDI diffusion and a reductive shift in poise of the calcium depleted endoplasmic reticulum
BMC Biol. 10;13(1):2(2015)
R. Ushioda, J. Hoseki, K. Nagata*.
Glycosylation-independent ERAD patway serves as a backup system under ER stress.
Mol Biol Cell. 24(20):3155-63 (2013)
R. Ushioda and K. Nagata*.
The endoplasmic reticulum-associated degradation and disulfide reductase ERdj5.
Methods Enzymol. 490:235-58 (2011)
M. Hagiwara, K. Maegawa, M. Suzuki, R. Ushioda, K. Araki, Y. Matsumoto, J. Hoseki, K. Nagata* and K. Inaba*
Structural basis of an ERAD pathway mediated by the ER-resident protein disulfide reductase ERdj5.
Mol Cell. 41(4):432-444(2011)
J. Hoseki, R. Ushioda and K. Nagata*.
Mechanism and components of endoplasmic reticulum-associated degradation.
Journal of Biochemistry 147(1):19-25(2010)
R.Ushioda, J.Hoseki, K.araki, G.Jansen , D.Y.Thomas, & K.Nagata*
ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER.
Science 321 (5888):569-72(2008)
この論文はBio Med Centralが提供するFACULTY OF 1000 BIOLOGYのMust Readに選定され、雑誌ACS CHEMICAL BIOLOGYのSpotlight（ACS CHEMICAL BIOLOGY vol.3 no.9 522-523, 2008）で特集された。国内でも読売新聞（2008年7月25日付2面）、朝日新聞（2008年7月25日付29面）、京都新聞（2008年7月25日付27面）などで報道された。
